Noscapine Base
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Stability: Stable under normal storage conditions (around 25°C, protected from light)
Pharmacokinetics:
- Absorption: Orally absorbed, but undergoes extensive first-pass metabolism in the liver, resulting in low bioavailability (around 3-5%).
- Distribution: Binds extensively to plasma proteins.
- Metabolism: Extensively metabolized in the liver to various metabolites, mostly inactive.
- Elimination: Primarily eliminated through the feces, with a small amount excreted in the urine.
- Half-life: Approximately 6-8 hours.
Pharmacological Actions:
- Antitussive: Suppresses cough reflex by acting on the cough center in the medulla oblongata.
- Bronchodilatory: Relaxes bronchial smooth muscle, but the effect is weak and of limited clinical significance.
- Vasodilatory: Dilates blood vessels, but the effect is weak and transient.
- Other: Weak analgesic, antihistaminic, and anti-inflammatory effects.
|
Assay |
99.85 |
|
Chemical Name |
Noscapine Base |
|
Physical State |
Powder |
Business Nature
Manufacturer
Country/Region
Istanbul, Turkey
Main Products
Pharmaceuticals...
Payment Terms
Cash, Bank wire (T/T)
PluviaEndo, a multinational pharmaceutical company headquartered in Istanbul, Turkey, is considering Raising the Healthcare rate with unique molecules and know-how. Our portfolio contains several specific APIs & Finished Dosage form medications in the field of various therapeutic categories (Addictions, Analgesics, Diabetic, CNS, Gastrointestinal, Nephrology, Respiratory, and Supplements) as well as Opioid medications & Nutraceutical Supplements. Since the Manufacturing/Procurement of our products is being done by ourselves and based on our own specific Know-How from A to Z, therefore, we can support you in documentation, formulation & scientific matters, in addition to supplying you with unique quality products at unrivaled prices (including different types of APIs & Finished dosage Forms).
